Article Id51 - How To Cure Toenail Fungus

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Current TB treatments must be taken over the course of several months and sometimes fail to fully eradicate the culprit bacteria. After systematically mining the resulting data-essentially, millions of pairwise interactions between different chemicals and essential genes-the researchers uncovered hundreds of compounds with previously unknown anti-TB activity. The researchers' new chemical finds, which are described in Nature, flow from an innovative, high-throughput drug discovery approach dubbed PROSPECT that can unearth promising drug candidates often missed by conventional methods. Johnson and his colleagues then used these pooled strains as the basis for a large-scale drug screening effort, which included a total of 150 hypomorphic strains and more than 50,000 chemical compounds, searching for chemicals that killed the weakened bacteria but left normal bacteria unscathed. For the most promising ones, they worked to optimize the chemicals' molecular structures in order to render the compounds lethal even for normal, non-vulnerable bacteria. Ideally, there are many different types of massage oils including the likes of coconut, olive, almond and jojoba oils

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